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Opana ER (extended release) is a prescription medication primarily used for the management of chronic pain in adults who require continuous, long-term opioid treatment. Containing the active ingredient oxymorphone, Opana ER is designed to provide sustained pain relief over an extended period, allowing patients to maintain a better quality of life. Given its potency, Opana ER is typically prescribed for those who have developed a tolerance to other opioid medications or for whom alternative treatment options have been ineffective